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. 2021 Jun 3;11:683951. doi: 10.3389/fonc.2021.683951

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Copyright © 2021 Du, Miao, Jiang, Cao, Wang, Wang, Yu, Wang and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of CALU as an independent risk factor of BLCA and construction of a prognostic nomogram including CALU level. (A, B) The univariate (p<0.001) and multivariate (p=0.002) Cox regression analysis confirmed CALU as an independent risk factor for BLCA. (C) A nomogram composed of CALU level, age and stage well indicated the OS of BLCA patients based on the nomogram scores, with a c-index of 0.678. (D) The calibration curve confirmed a pleasant accuracy of the nomogram in predicting 1,3 and 5 years’ OS.