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. 2021 Jun 3;12:653901. doi: 10.3389/fphar.2021.653901

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Copyright © 2021 Zhang, Zhang, Wang, Han, Liu, Li, Chen, Liu, Wang, Tian, Zhao and Yan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BCW treatment alleviated ISO-induced myocardial hypertrophy. (A) Gross hearts from all groups of rats. (B and C) Quantification of heart weight to body weight ratio and left ventricle heart weight to body weight ratio. (D and E and F) Real-time polymerase chain reaction analysis of the mRNA expression of ANF, BNP, and β-MHC. Data were normalized by GADPH for mRNA expression and presented as mean ± SE, *p < 0.05 vs. control, **p < 0.01 vs. control;^# p < 0.05 vs. ISO, ^## p < 0.01 vs. ISO, n = 10.