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. 2021 Jun 3;12:653901. doi: 10.3389/fphar.2021.653901

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Copyright © 2021 Zhang, Zhang, Wang, Han, Liu, Li, Chen, Liu, Wang, Tian, Zhao and Yan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BCW attenuated ISO-induced cardiac functional remodeling. (A) Representative M-mode tracings of echocardiography after 5 weeks of the whole experiments. (B–K) Quantification echocardiographic parameters: (B) heart rate (HR); (C) ejection fraction (E,F); (D) fractional shortening (FS); (E) left ventricular anterior wall at diastole (LVAWd); (F) left ventricular anterior wall at systole (LVAWs); (G) left ventricular posterior wall thickness at diastole (LVPWd); (H) left ventricular posterior wall thickness at systole (LVPWs) (I) left ventricular internal dimension at diastole (LVIDd); and (J) left ventricular internal dimension at systole (LVIDds); the data were expressed as the mean ± SE. *p < 0.05 vs. control, **p < 0.01 vs. control; ^# p < 0.05 vs. ISO, ^## p < 0.01 vs. ISO, n = 10 in each group.