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. 2021 Jun 3;12:653901. doi: 10.3389/fphar.2021.653901

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Copyright © 2021 Zhang, Zhang, Wang, Han, Liu, Li, Chen, Liu, Wang, Tian, Zhao and Yan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BCW suppressed myocardial hypertrophy induced by ISO. (A) Representative slides of cardiac cross sections by hematoxylin and eosin; scale bar in A = 2000 μM, magnification (10×), scale bar in B = 100 μM, magnification (200×). (B) cross-sectional area (CSA) of cardiomyocytes, (C and D) The levels of CK and LDH in serum were measured by commercial kit, respectively. Results are shown as the mean ± SE. *p < 0.05 vs. control, **p < 0.01 vs. control; ^# p < 0.05 vs. ISO,^## p < 0.01 vs. ISO, n = 10 in each group.