TABLE 1.
Some genes/proteins differentially regulated in C. acetobutylicum biofilms*.
| Genes/proteins | General change | Description |
| Glycolysis | ||
| CA_C0570 (glcG) | Up-regulated | PTS sugar transporter subunit |
| CA_C3657 (gapN) | Up-regulated | NADP+-dependent Glyceraldehyde-3-phosphate dehydrogenase |
| CA_C0712 (pgm) | Up-regulated | Phosphoglycerate mutase |
| CA_C0713 (eno) | Up-regulated | Enolase |
| CA_P0141-0142, CA_C0809-0810 | Up-regulated | Hydrogenases and maturation factors |
| CA_C3552 (ldh) | Up-regulated | L-lactate dehydrogenase |
| CA_C2967 (alsD) | Down-regulated | α-Acetolactate decarboxylase |
| Pentose metabolism | ||
| CA_C1339-1341 (araEAD) | Up-regulated | L-arabinose utilization |
| CA_C2610, CA_C3451 | Up-regulated | D-xylose utilization |
| CA_C1343 (xfp) | Up-regulated | Phosphoketolase |
| CA_C1347-1348 (tkt, tal) | Up-regulated | Pentose phosphate pathway |
| Polysaccharides metabolism | ||
| CA_C2383, CA_C0358 | Up-regulated | Xylanase/chitin deacetylase |
| CA_C0804, CA_C1968 | Up-regulated | Pectate lyase |
| CA_C0910 | Up-regulated | Cellulosomal scaffolding protein |
| Iron and sulfur assimilation | ||
| CA_C0788-0791, CA_C1029-1030 | Up-regulated | Iron assimilation |
| CA C0102-0110 | Up-regulated | SULFATE assimilation |
| Sporulation and chemotaxis | ||
| CA_C2086-2093, CA_C2859 (spoIIID) | Up-regulated at early stages then down-regulated over time | Stage III sporulation proteins |
| CA_C1487, CA_C2365 | Down-regulated | Small acid-soluble spore protein |
| CA_C2908-2910, CA_C1337-1338 | Down-regulated | Spore coat protein |
| CA_C0117 | Up-regulated | CheY-like chemotaxis protein |
| CA_C2745, CA_C2419, CA_C2803 | Down-regulated | Methyl-accepting chemotaxis protein |
| CA_C2205 (fliD) | Down-regulated | Flagellar hook-associated protein |
| Oxidative stress response | ||
| CA_C1547-1549 | Up-regulated at early stages then down-regulated over time | Thioredoxin and thioredoxin reductase |
| CA_C1570-1571 | Up-regulated at early stages then down-regulated over time | Glutathione peroxidase |
| CA_C3597-3598 | Up-regulated at early stages then down-regulated over time | Reverse rubrerythrin |
| Others | ||
| CA_C0252-0255 | Up-regulated | Nitrogen-fixation |
| CA_C0280-0281 | Up-regulated | Molybdate transporter |
| CA_C3634-3644 | Up-regulated | Oligopeptide transporter |
| CA_C1447, CA_C1504, CA_P0109, CA_P0128 | Down-regulated | MDR-type permease |
*Results are summarized from the studies of Liu et al. (2016, 2018) and Yang et al. (2020).