Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Antisense oligonucleotides in IBD treatment.
| Antisense oligonucleotides for IBD treatment | |
| Target of AONs | Administration approach |
| Intracellular adhesion molecule-1 (alicaforsen) (Jairath et al., 2017) | Intravenous, rectal |
| Inhibition of Smad7 (mongersen) (Boirivant et al., 2006) | Oral |
| NF-κBp65 (Murano et al., 2000) | Intracolonic |
| Blocking CD154/CD40 interactions (Gao et al., 2005) | Intracolonic |
| TNF-α (Duan et al., 2019) | Oral |
