FIGURE 7.

GlcN suppressed inflammatory responses in colon tissues of HFD-fed mice. After the treatment with NCD, HFD, and/or GlcN (1 mg/ml, in drinking water) for 5 months, all mice were sacrificed. The colon tissues were stained by H&E and photographed under a microscope (magnification of ×100, ×200 and ×400) (A). The expressions of MCP-1 (B), IL-6 (C), and IL-1β (D) in colon at mRNA level were detected by qRT-PCR. Data were shown as means ± SEM (n = 5). *p < 0.05 indicates the difference between HFD group and NCD group; ^## p < 0.01 indicates the difference between HFD + GlcN group and HFD group.