Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pluripotency genes in the regulation of tumor properties. Several tumor microenvironment factors and extracellular matrix components activate different signaling pathways that regulate the expression of OCT4, SOX-2, and NANOG. They either act alone or together for the transcriptional activation of genes responsible for CSC self-renewal, EMT, metastasis, cell survival, and chemoresistance.
