FIGURE 1.

Genetic variation and expression of m⁶A regulators in ovarian cancer. (A) The mutation frequency of m⁶A regulators in ovarian cancer available at TCGA database by using maftools package. (B) Copy number variations of m⁶A regulators in ovarian cancer available at TCGA database by using cBioPortal (http://cbioportal.org). (C) The mutation co-occurrence and exclusion analysis for m⁶A regulators. (D) The copy number variation co-occurrence and exclusion analysis for m⁶A regulators. (E) The mRNA expression alterations of m⁶A regulators in four independent GEO microarray datasets. (F) The mRNA expression of m⁶A regulators in GSE27651 cohort. HOSE, human ovarian surface epithelium, OVC, ovarian cancer. *P < 0.05, **P < 0.01, ***P < 0.001.