FIGURE 7.
Predicted class probabilities of the validation cohort samples. (A) The probabilities were calculated based on the 10-gene Lasso model estimated on the full training data. The validation cohort included 18 pure DCIS cases, 20 IBC cases, and 16 micro-invasive (MI) DCIS cases. Note: y-axis is log-scaled for better visualization. The non-logged version is shown in Supplementary Figure 8. (B) The probabilities were calculated based on the six microenvironment related genes. The validation cohort included 14 DCIS cases without recurrence, four DCIS recurrence cases, and 20 IBC cases. The y-axes are z-scaled for better comparability of the prediction probabilities. The horizontal lines in the boxplots indicate median values, the whiskers the interquartile range (IQR) of the cases in each class, and the error bars show cases withing 1.5xIQR, while the remaining cases are considered outliers.
