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. 2021 May 13;10(12):4030–4045. doi: 10.1002/cam4.3959

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© 2021 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Biological interaction network and clinical significance of IBSP in CRC. (A) The correlations between IBSP and the differentially expressed genes in CRC. (B) According to the GSEA in GSE17538 dataset, cell‐matrix adhesion gene set was correlated with metastatic recurrence in CRC. (C) The correlation of IBSP and representative cell‐matrix adhesion‐related genes in the GSE17538 dataset. (D) IBSP expression was correlated with survival of CRC patients. Low expression of IBSP conferred a survival advantage to CRC patients