FIGURE 7.

The mechanisms of IBSP function in CRC. *p < 0.05; **p < 0.01; ns: nonsignificant. (A) The LYN mRNA expression following IBSP downregulation. (B) The FYN mRNA expression following IBSP downregulation. (C) The LCK mRNA expression following IBSP downregulation. (D) Protein level of Fyn, p‐Fyn, and p‐β‐catenin decreased after transfection of IBSP‐siRNA, while β‐catenin showed no significant variation. (E) The expression of IBSP was significantly positively correlated with the expression of Fyn and β‐catenin