TABLE 3.
Lesion characteristics
| Total number of lesions | 662 |
| Tumor location | |
| Oropharynx | 132 (19.9%) |
| Anterior wall / Posterior wall / Lateral wall / Superior wall | 9/79/23/21 |
| Hypopharynx | 519 (78.4%) |
| Postcricoid / Pyriform sinus / Posterior wall | 33/404/82 |
| Larynx | 7 (1.1%) |
| Laryngeal epiglottis / Laryngeal arytenoid / Aryepiglottic folds | 4/2/1 |
| Oral cavity | 4 (0.6%) |
| Oral floor / Hard palate / Buccal mucosa | 1/1/2 |
| Macroscopic type | |
| Flat / Elevated / Unknown | 528 (79.8%) / 127 (19.2%) / 7 (1.1%) |
| Treatment methods | |
| Endoscopic mucosal resection (EMR) | 307 (46.2%) |
| Endoscopic submucosal dissection (ESD) | 264 (39.7%) |
| Endoscopic laryngopharyngeal surgery (ELPS) | 31 (4.7%) |
| Transoral videolaryngoscopic surgery (TOVS) | 31 (4.7%) |
| Laser microlaryngeal surgery | 17 (2.6%) |
| Direct mucosectomy | 12 (1.8%) |
| Number of resected specimens | |
| En bloc | 490 (74.0%) |
| Piecemeal | 172 (26.0%) |
| Number of segments obtained by piecemeal resection | |
| 2/3/4/5/6/7/8/9/10/11 | 85/39/13/11/10/7/3/1/2/1 |
| Tumor diameter on endoscopic images, median (range) a | 12 (1–75) |
| Tumor diameter of resected specimens, median (range) b | 14 (1–60) |
| EMR / ESD / ELPS / TOVS / Other procedures | 12 (1–45) / 15 (1–60) / 20 (2–58) / 16 (5–42) / 13 (3–50) |
| Endoscopic depth of invasion for resected lesions | |
| Intraepithelial / Subepithelial / Difficult to evaluate | 472 (71.0%) / 158 (23.8%) / 32 (4.8%) |
| Histopathological depth of invasion (central diagnosis) | |
| Intraepithelial / Subepithelial | 380 (57.4%) / 282 (42.6%) |
| T category | |
| Tis / T1 / T2 / T3 / Unknown | 380 (57.4%) / 181 (27.3%) / 89 (13.4%) / 11 (1.7%) / 1 (0.2%) |
| Lymphatic invasion | 19 (2.9%) |
| Venous invasion | 16 (2.4%) |
| Horizontal margin positive for cancer in the resected specimen | 309 (46.7%) |
| Subsequent treatment immediately after initial transoral surgery | 20 (3.0%) |
a
Missing data for 29 patients.
b
Missing data for 1 patient.