Table 1.
Patient demographic and clinical profiles
|
Factor |
Category |
Total (%) |
Lineage 1 |
Lineage 2 |
Lineage 4 |
P-value |
|---|---|---|---|---|---|---|
|
Admission status |
Inpatient |
61 (28.6) |
57 |
2 |
2 |
|
|
Outpatient |
152 (71.4) |
139 |
11 |
2 |
0.338 |
|
|
Sputum microscopy |
Positive |
164 (83.7) |
148 |
13 |
3 |
|
|
Negative |
32 (16.3) |
31 |
0 |
1 |
0.198 |
|
|
|
nd |
17 |
17 |
0 |
0 |
|
|
No. of isolates involved in genomic clusters |
Yes |
27 (12.7) |
21 |
4 |
2 |
0.013 |
|
No |
186 (87.3) |
175 |
9 |
2 |
||
|
Age (years) |
<18 |
12 (8) |
11 |
1 |
0 |
0.486 |
|
19–29 |
58 (38.7) |
54 |
2 |
2 |
||
|
30–39 |
26 (17.3) |
23 |
3 |
0 |
||
|
>40 |
54 (36) |
49 |
5 |
0 |
||
|
nd |
63 |
59 |
2 |
2 |
||
|
Sex |
Female |
63 (41.2) |
58 |
3 |
2 |
0.672 |
|
Male |
90 (58.8) |
80 |
8 |
2 |
||
|
nd |
60 |
58 |
2 |
0 |
||
|
Body mass index (kg m−2) |
<18 |
75 (55.6) |
64 |
10 |
1 |
0.166 |
|
19–24 |
51 (38.6) |
50 |
1 |
0 |
||
|
25–30 |
6 (4.5) |
6 |
0 |
0 |
||
|
>30 |
1 (0.8) |
1 |
0 |
0 |
||
|
Mean |
18.5 |
|||||
|
nd |
80 |
75 |
2 |
3 |
||
|
Culture+ at 8 weeks |
Yes |
8 (8.8) |
4 |
4 |
0 |
<0.001 |
|
No |
82 (91.1) |
78 |
3 |
0 |
||
|
nd |
118 |
114 |
2 |
4 |
||
|
HIV status |
Positive |
2 (1.5) |
2 |
0 |
0 |
0.995 |
|
Negative |
133 (98.5) |
121 |
11 |
1 |
||
|
nd |
78 |
73 |
2 |
3 |
||
|
Haemoptysis |
Yes |
35 (26.1) |
30 |
5 |
0 |
0.239 |
|
No |
99 (73.9) |
92 |
6 |
1 |
||
|
nd |
79 |
74 |
2 |
3 |
||
|
Smoking |
Yes |
69 (49.3) |
63 |
6 |
0 |
0.884 |
|
No |
71 (50.7) |
65 |
5 |
1 |
||
|
nd |
73 |
68 |
2 |
3 |
||
|
Presence of cavity |
Yes |
51 (52.6) |
42 |
8 |
1 |
0.414 |
|
No |
46 (47.4) |
42 |
3 |
1 |
||
|
nd |
116 |
112 |
2 |
2 |
||
|
Country of birth |
Malaysia |
100 (65.8) |
91 |
7 |
2 |
0.568 |
|
Indonesia |
6 (3.9) |
5 |
1 |
0 |
||
|
Philippines |
46 (30.3) |
43 |
3 |
0 |
||
|
nd |
61 |
57 |
2 |
2 |
nd, not determined; P-values calculated using Fisher’s exact test.