Table 5.
Multivariable regression analysis for significant associations between evaluated variables and plasma osteopontin (pOPN), as well as CCA IMT in the SLE patients (n = 60).
|
Univariate analysis |
Multivariable analysis |
|||
|---|---|---|---|---|
| Risk factors | B | P value | B | P value |
| pOPN | ||||
| SLE duration | 0.63 | 0.04 | –0.24 | 0.50 |
| SDI score | 9.74 | 0.00 | 7.02 | 0.04 |
| hsCRP | 2.16 | 0.03 | 1.55 | 0.10 |
| Raynaud | 12.37 | 0.05 | 8.12 | 0.15 |
| Warfarin | 22.0 | 0.002 | 13.27 | 0.08 |
| CCA IMT | ||||
| SDI score | 0.03 | 0.01 | 0.010 | 0.44 |
| Tobacco smoking (ever) | 0.09 | 0.01 | 0.06 | 0.05 |
| Triglycerides | 0.06 | 0.00 | 0.04 | 0.04 |
| Antimalarials | –0.12 | 0.01 | –0.07 | 0.10 |
| Warfarin | 0.07 | 0.05 | 0.01 | 0.81 |
hsCRP: high-sensitivity C-reactive protein; SDI: SLICC/ACR damage index; SLE: systemic lupus erythematosus.
Note: Statistically significant associations shown in bold.