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. 2021 Jun 2;93(23):8143–8151. doi: 10.1021/acs.analchem.0c05311

Table 1. Major Differential Lipids and Metabolites between Individual Cell Marker Typesa.

  CD31 CD68 CD20 histone pancytoleratin Ki67
CD68 NAPE(58:5p)          
  CL 72:8          
  CL 76:11          
  citrate/isocitrate          
  GM3(16:0h)          
CD20 NAPE(58:5p) LysoPA(16:0) [M–H2O–M]        
  CL 76:11 GM3(24h:0)        
  CL 78:13 PEp 40:6        
  hexose PE 36:3        
  arginine LysoPA 18:1 [M–H2O–M]        
histone CL 72:8 PE 36:3 PE 36:3      
  NAPE(58:5p) PI 40:6 GM3(24h:0)      
  PI 40:6 GM3(24:0) FA_C22:5      
  hexose monophosphate [M–H] citrate/isocitrate citrate/isocitrate      
  PA(38:3) LysoPSp 18:1 NAPE(52:5p)      
  PI 40:6 PS 38:4 PI 34:1 PE 34:1    
pancytoleratin CL 72:8 LysoPA(16:0) [M–H2O–M] PI 36:1 PS 38:4    
  hexose monophosphate [M–H] PI 40:6 PI 40:6 PI 40:6    
  NAPE(58:5p) PI 36:2 PS 38:4 LysoPI 18:0 [M–H2O–M]    
  PI 36:1 PE 36:3 NAPE(52:5p) PI 34:1    
Ki67 NAPE(58:5p) CL 74:10 CL 74:10 LysoPSp 18:1 PI 36:2  
  CL 72:8 CL 78:13 LysoPSp 18:1 PI 36:1 PI 36:1  
  CL 78:13 LysoPA 18:1 [M–H2O–M] FA_C22:1 NAPE(58:6p) PS 38:4  
  CL 74:10 CL 78:7 CL 78:1 FA_C22:1 FA_C22:1  
  PE 38:4 NAPE(58:5p) PI 36:1 PI 36:2 PI 34:1  
CD45 CL 74:5 CL 76:5 CL 76:5 CL 76:5 PI 40:6 CL 74:5
  CL 76:5 CL 74:5 CL 74:5 CL 74:5 CL 74:5 CL 76:5
  arginine arginine PE 38:3 PI 40:6 FA_C20:3 PE 38:4
  NAPE(56:5p) NAPE(56:5p) PE 38:4 FA_C20:3 CL 76:5 PEp 40:5
  GM3(16:0h) PE 42:7 hex(3)-hexNAc(3)-cer 44:1 GM3(16:0h) LysoPI 18:0 [M–H2O–M] PEp 38:4
a

Matrix showing the top five known species that showed differences between two markers. Top species were identified using the VIP score from OPLS-DA analysis.