Table 1.
Delafloxacin and comparator activity against S. pneumoniae serotypesa from blood and bronchoalveolar lavage
| Antibiotic | MIC50 (mg/L) | MIC90 (mg/L) | MIC range (mg/L) | Susceptible (%) |
|---|---|---|---|---|
| Delafloxacin | 0.015 | 0.015 | 0.008–0.015 | 100 |
| Moxifloxacin | 0.25 | 0.25 | 0.12–0.25 | 100 |
| Azithromycin | 0.25 | 0.25 | 0.12–>32 | 90.9 |
| Penicillinb | ≤0.03 | ≤0.03 | ≤0.03 | 100 |
| Clindamycin | 0.06 | 0.12 | 0.06–>32 | 90.9 |
| Ceftriaxone | 0.015 | 0.03 | 0.015–0.03 | 100 |
a
The S. pneumoniae serotypes and numbers of isolates were: 9N (n = 1); 18C (n = 1); 4 (n = 3); 1 (n = 2); 9V (n = 1); 23F (n = 1); 3 (n = 1); and 12F (n = 1).
b
CLSI oral penicillin breakpoints.20