Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 31;2(3):zcaa014. doi: 10.1093/narcan/zcaa014

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020. Published by Oxford University Press on behalf of NAR Cancer.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 1. — MiR-21-5p is the most abundant oncomiR across cancer. (A) Heat map showing the expression (log₂ RPM) of the 200 most abundant miRNAs in indicated TCGA miRNA-seq data sets. miRNAs are ranked according to the median log₂ RPM across all data sets. Numbers of patients in each cohort are indicated in the bottom panel. Sequencing data are summarized in Supplementary Table S1. (B) Pie charts indicating the percentage distribution of miRNAs in all TCGA (left) and LUAD (right) miRNA transcriptomes. (C) Box plots of miRNA expression in lung (blue, n = 45) or LUAD (red, n = 519) data sets. Statistical significance indicated by P-values was determined by the Mann–Whitney test. (D) Kaplan–Meier plots of overall survival analyses based on expression (best cutoff) of indicated miRNAs in LUAD patient samples. HR, hazard ratio; p, log-rank P-value.