Table 1.
Phenotypic and genotypic characteristics of MRSA isolates in this study
| Isolate | County | mec gene | ST | spa type | Oxacillin |
Cefoxitin |
Penicillin |
Cefalotin | Human immune evasion cluster |
|||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IZD (mm) | VITEK | IZD (mm) | VITEK | IZD (mm) | VITEK | VITEK | chp | scn | sak | |||||
| QM059 | North Yorkshire | mecC | 4652 | t843 | 7 | R | 18 | R | 15 | R | R | − | − | − |
| QM212 | Somerset | mecA | 5 | t002 | 6 | R | 10 | R | 6 | R | R | + | + | + |
| QM312 | Shropshire | mecA | 398 | t034 | 6 | R | 15 | R | 6 | R | R | + | + | + |
| QM355 | Shropshire | mecC | 425 | t10855 | 11 | R | 20 | R | 14 | R | R | − | − | − |
| QM518 | Devon | mecC | 425 | t6292 | 6 | R | 18 | R | 10 | R | R | − | − | − |
| QM652 | Pembrokeshire | mecC | 425 | t6292 | 6 | R | 17 | R | 10 | R | R | − | − | − |
IZD, inhibition zone diameter; R, resistant.
6 mm in disc diffusion indicates no inhibition zone.
For penicillin, resistant breakpoint for disc diffusion is <26 mm diameter.
For cefoxitin, resistant breakpoint for disc diffusion is <22 mm diameter.
For oxacillin, resistant breakpoint for disc diffusion is ≤14 mm diameter (BSAC).
spa types were determined from the sequencing data using spaTyper 1.0 (https://cge.cbs.dtu.dk/services/spaTyper-1.0/).