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. 2021 Jun 8;22(2):851. doi: 10.3892/etm.2021.10283

Figure 2.

Figure 2

Effects of STK10 KO on the proliferation, apoptosis and migration of PCa cells. (A) BrdU incorporation and FACS analyses for control and STK10-KO DU145 cells. (B) Effects of STK10 KO on the apoptosis of DU145 cells were examined by Annexin V-FITC/PI staining. (C) Proliferative activity of control and STK10-KO DU145 cells was quantified using a Cell Counting Kit-8 assay. (D and E) The percentages of different stages of the cell cycle and apoptotic cells were calculated. n=3 in each group. All experiments were performed at least three times. (F and G) Representative images and quantitative analysis of the Transwell migration assays. Magnification, x100. Data are presented as the mean ± standard deviation. *P<0.05, **P<0.01, ***P<0.001 vs. Ctrl. STK10, serine threonine kinase 10; KO, knockout; PCa, prostate cancer; FACS, fluorescence activated cell sorting; AAD, 7-amino actinomyosin D; Ctrl, control.