Table 2.
Phenotypic characteristics of men with NOA related to Klinefelter syndrome (n = 19) according to the testicular sperm extraction outcomes
| Overall Klinefelter syndrome individuals n = 19 |
Positive sperm retrieval n = 6 |
Negative sperm retrieval n = 13 |
P-value | |
|---|---|---|---|---|
|
Age at TESE (years) ¤ [median (IQR)] |
30 (28–34) |
29.5 (24-34.2) |
30 (28–35) |
0.63 |
|
Mean testicular volume (mL) ¤ [median (IQR)] |
2.7 (2-3.5) |
3.1 (1.9–4.3) |
2.5 (2-3.3) |
0.21 |
|
FSH (IU /L) ¤ [median (IQR)] |
30.5 (18.9–36.7) |
29.9 (18.3–34.8) |
30.9 (21.8–36.9) |
0.61 |
|
LH (IU /L) ¤ [median (IQR)] |
12.4 (9.8–15.9) |
11.7 (9.4–15.2) |
12.4 (9.8–17) |
0.75 |
|
Testosterone (ng/ml) ¤¤ [median (IQR)] |
2.6 (1.7–3.6) |
3 (2.8–4.5) |
1.8 (1.2–3.6) |
0.14 |
|
AMH (pmol/l) ¤¤ [median (IQR)] |
2.3 (1.1-8.6) |
8 (3–13) |
1.7 (0.8–4.7) |
0.01 |
| AMH/Testosterone ¤¤ [median (IQR)] |
0.14 (0.1–0.3) |
0.3 (0.1–0.4) |
0.1 (0.08–0.2) |
0.06 |
|
Inhibin B (pg/ml) ¤¤ [median (IQR)] |
8 (8–10) |
8 (8–14) |
8 (8–10) |
0.60 |
Statistical analysis was performed by the two-tailed Student’s t (¤) or Mann Whitney U (¤¤) tests
IQR Interquartile range (first and third quartiles), NOA Nonobstructive azoospermia