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. 2021 Jun 16;14:162. doi: 10.1186/s12920-021-01007-9

Table 1.

IA risk associated SNPs and the associated linkage disequilibrium blocks

Sentinel SNP SNP Location Nearest Gene LD Block (hg38) Length (bp)
rs3767137 Intronic HSPG2 chr1:21834230–21841817 7587
rs1800255 Exonic COL3A1 chr2:188976887–189003156 26,269
rs1429412 Intergenic ANKRD44 chr2:197283467–197358397 74,930
rs700651 Intronic BOLL chr2:197676674–197766990 90,316
rs6841581 Intergenic EDNRA chr4:147444187–147493499 49,312
rs251124 Intronic VCAN chr5:83509605–83530435 20,830
rs4628172 Intronic AGMO chr7:15454259–15466904 12,645
rs1800796 Intronic IL6 chr7:22726627–22732119 5492
rs42524 Exonic COL1A2 chr7:94413927–94420044 6117
rs10958409 Intergenic chr8:54397171–54415556 18,385
rs9298506 Intergenic chr8:54509054–54549764 40,710
rs2891168 Intronic CDKN2B-AS1 chr9:22072265–22125504 53,239
rs10757278 Intergenic CDKN2B-AS1 chr9:22077086–22125504 48,418
rs6538595 Intronic FGD6 chr12:95095355–95123067 27,712
rs4934 Exonic SERPINA3 chr14:94612340–94614466 2126
rs1132274 Exonic RRBP1 chr20:17613385–17619469 6084

Bolded SNPs were chosen as examples in Fig. 1, Fig. 2, and Additional file 1: Fig. S1

hg, human genome; IA, intracranial aneurysm; rs, reference SNP cluster ID; SNP, single nucleotide polymorphism; chr, chromosome; LD, linkage disequilibrium