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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Exp Neurol. 2021 May 13;342:113765. doi: 10.1016/j.expneurol.2021.113765

Figure 1. TBI prior to cerebral ischemia exacerbates infarct volume, edema, and functional deficits.

Figure 1.

A) Mice that underwent a TBI 7 days prior to MCAO exhibited a significantly greater infarct volume, compared to those that had a control (CON) procedure prior to MCAO. B) Representative TTC stained tissue throughout the forebrain indicating healthy (red) and infarcted (white) tissue in the cortex and striatum. C) Mice that underwent a TBI prior to MCAO also exhibited significantly greater edema. D) Right-biased turning in the corner test revealed significant deficits in mice that underwent both a TBI and MCAO. Data are presented as mean +/− SEM. An asterisk (*) indicates significance at p < 0.05.