. Author manuscript; available in PMC: 2022 Jun 15.

Published in final edited form as: Circ Cardiovasc Imaging. 2021 Jun 15;14(6):e009025. doi: 10.1161/CIRCIMAGING.121.009025

Table 4 –

Imaging parameters associated with poorer prognosis in cardiac amyloidosis seen on both echocardiography and cardiac magnetic resonance (CMR).

Parameters – Echocardiography	Thresholds associated with worse prognosis
Global longitudinal strain (GLS)	−12% or greater (less negative) ^*
Apical/basal strain ratio	2.1 or more
Mitral annular plane systolic excursion (MAPSE)	8.8mm or less
Tricuspid annular plane systolic excursion (TAPSE)	14mm or less
Myocardial contraction fraction	0.25 or less

Parameters – CMR
Pre-contrast myocardial T1 (1.5 T field strength; using shMOLLI)	> 1044ms
Extra-cellular volume (ECV)	> 0.45
Late-gadolinium enhancement (LGE)	Transmural pattern

Thresholds for each parameter based on available data is shown (shMOLLI: Shortened Modified Look Lockers Inversion).

cut-offs used for prognosis in current studies range between −10% to 14%