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PTX3 negatively regulates IL4 and IL10 expression via inhibiting JNK1/2 phosphorylation in gastric cancer cells. (A, B) The mRNA levels of IL4 and IL10 in BGC-823 and SGC-7901 cells after upregulating PTX3 were checked by qRT-PCR. (C, D) BGC-823 and SGC-7901 cells were transfected with PTX3 overexpression plasmid (PTX3) and a negative control plasmid (CTL). Detection of IL4, IL10, JNK1/2 and p-JNK1/2 via western blot assay (*P < 0.05, **P < 0.01).
