Table 1.
Correlation between the clinicopathological features and MST4 expression in 325 HCC tissue specimens
| Variables | Case No. | MST4 expression | χ2 | P | |
|---|---|---|---|---|---|
| (n) | High (n, %) | Low (n, %) | |||
| Gender | |||||
| Female | 60 | 20 (33.3) | 40 (66.7) | 0.745 | 0.38 |
| Male | 265 | 107 (40.4) | 158 (59.6) | ||
| Age (years) | |||||
| <50 | 158 | 57 (36.1) | 101 (63.9) | 0.931 | 0.307 |
| ≥50 | 167 | 70 (41.9) | 97 (58.1) | ||
| Histological grade | |||||
| I-II | 97 | 60 (61.9) | 37 (38.1) | 28.79 | <0.001 |
| III-IV | 228 | 67 (29.4) | 161 (70.6) | ||
| T classification | |||||
| T1-T2 | 225 | 99 (44.0) | 126 (56.0) | 6.788 | 0.007 |
| T3-T4 | 100 | 28 (28.0) | 72 (72.0) | ||
| N classification | |||||
| N0 | 305 | 124 (40.7) | 181 (59.3) | 5.189 | 0.031 |
| N1 | 20 | 3 (15.0) | 17 (85.0) | ||
| M classification | |||||
| M0 | 313 | 125 (39.9) | 188 (60.1) | 2.629 | 0.136 |
| M1 | 12 | 2 (16.7) | 10 (83.3) | ||
| Clinical stage | |||||
| I-II | 208 | 97 (46.6) | 111 (53.4) | 13 | <0.001 |
| III-IV | 117 | 30 (25.6) | 87 (74.4) | ||
T: tumor size; N: lymph node metastasis; M: distant metastasis.