Table 1.
Demographic and clinical characteristics
| Variables | Median (IQR), or n (%) |
|---|---|
| Age, years | 69.0 (62.0-75.0) |
| Sex | |
| Male | 136 (63.6) |
| Female | 78 (36.4) |
| Smoker | |
| Current | 42 (19.6) |
| Former | 86 (40.2) |
| Never | 86 (40.2) |
| ECOG PS | |
| 0/1 | 206 (96.3) |
| 2 | 8 (3.7) |
| Percent predicted FEV1 | 102.3 (90.0-115.0) |
| BMI, kg/m2 | 23.7 (21.8-25.8) |
| Types of surgery | |
| Pneumonectomy/lobectomy | 168 (78.5) |
| Segmentectomy | 46 (21.5) |
| Histology | |
| Adenocarcinoma | 151 (70.6) |
| Squamous cell carcinoma | 55 (25.7) |
| Others† | 8 (3.7) |
| Size of tumor, cm | 2.7 (1.9-3.5) |
| T-stage | |
| pT1 | 100 (46.8) |
| pT2 | 97 (45.3) |
| pT3 | 17 (7.9) |
| N-stage | |
| pN0 | 197 (92.1) |
| pN1 | 17 (7.9) |
| TNM Stage‡ | |
| IA/IB | 163 (76.2) |
| IIA/IIB | 51 (23.8) |
| Pleural invasion | |
| PL0 | 157 (73.4) |
| PL1/2/3 | 57 (26.6) |
| Lymphatic invasion | |
| No | 193 (90.2) |
| Yes | 21 (9.8) |
| Vascular invasion | |
| No | 204 (95.3) |
| Yes | 10 (4.7) |
| Albumin, g/dL | 4.1 (3.9-4.3) |
| Anemia§ | |
| No | 143 (66.8) |
| Yes | 71 (33.2) |
| CLR | 0.8 (0.4-2.6) |
† Adenosquamous cell carcinoma (3 cases), pleomorphic carcinoma (3 cases), and large cell carcinoma (2 cases).
‡ AJCC 8th edition.
§ The cutoff point is 12 g/dL for female patients and 13 g/dL for male patients.
IQR, interquartile range; ECOG PS, Eastern Cooperative Oncology Group performance status; FEV1, forced expiratory volume in one second; BMI, body mass index; PL, pleural invasion; TNM, tumor-node-metastasis; CLR, CRP to lymphocyte ratio.