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. 2021 Jun 4;12(15):4661–4671. doi: 10.7150/jca.53115

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The expression level of ApoM in cancer tissues is lower than that in adjacent tissues. (A) 50 matched samples of primary liver cancer were selected from the TCGA database. The analysis showed that the expression level of ApoM gene in cancer tissues was lower than that in paracarcinoma tissues, and the difference was statistically significant (P=0.025). (B) Using immunohistochemical method to detect the expression level of ApoM in cancer tissues and adjacent tissues of liver cancer patients, the expression level of ApoM in cancer tissues decreased significantly (P=0.0063). (C) The expression level of ApoM in the normal mouse liver cell line AML12 was higher than that in the mouse liver cancer cell line Hepa1-6 (P=0.012) *p<0.05, **p<0.03, ***p<0.01.