Table 2.

Experimentally studied Host proteins/lipids that can regulate the plasmodesmata for plant defense.

Proteins/lipids	Function	References
LYM2-LYK4	PD located LYM2-LYK4 recognize the chitin and trigger downstream signaling to reduce the molecular flux through PD.	Faulkner et al., 2013; Cheval et al., 2020
FLS2	FLS2 is observed in the vicinity of PD and mediates flg22-triggered changes of PD-mediated trafficking.	Faulkner et al., 2013
RBOHD	RBOHD produce ROS that induces PD closure in the signaling cascade of LYM2-LYK4.	Cheval et al., 2020
CalS1	Callose deposition	Dong et al., 2008; Cui and Lee, 2016
CalS12	Callose deposition	Dong et al., 2008
PDLP1	Callose deposition	Caillaud et al., 2014
PDLP5	Callose deposition	Lee et al., 2011; Wang et al., 2013
Calreticulin	Calreticulin interact directly with TMV MP and interferes with targeting of TMV MP to delay cell-to-cell movement of the virus.	Chen et al., 2005
Remorins	Remorins interact with MP TGBp1 of PVX and impairs PVX movement.	Raffaele et al., 2009
	Remorins narrow the PD channels to impede virus spreading depended on SA signaling.	Huang et al., 2019
Sphingolipids	Sphingolipids recruited PDLP5 proteins to PD, which consequently results in the decreased PD conductivity.	Liu et al., 2020