. 2021 Jun 3;15:642349. doi: 10.3389/fnsys.2021.642349

TABLE 1.

Demographic and clinical information of the PDM subjects and controls used in human MRI.

	Resting-state fMRI (M ± SD)			Task fMRI (M ± SD)			Structural MRI (M ± SD)

	PDM (n = 35)	Ctrl (n = 38)	p value	PDM (n = 30)	Ctrl (n = 31)	p value	PDM (n = 38)	Ctrl (n = 42)	p value
Age, years^a	20.49 ± 1.20	20.58 ± 1.52	0.694	20.70 ± 1.12	20.45 ± 1.06	0.326	20.55 ± 1.22	20.60 ± 1.47	0.633
Age of onset of menstruation, years^a	12.60 ± 1.31	13.05 ± 1.51	0.196	12.53 ± 1.31	12.32 ± 2.75	0.952	12.63 ± 1.28	12.95 ± 1.50	0.364
Menstrual duration, years^a	7.89 ± 1.75	7.53 ± 1.70	0.417	8.17 ± 1.76	8.13 ± 2.90	0.479	7.92 ± 1.71	7.64 ± 1.66	0.551
Menstrual cycle, days^a	30.63 ± 2.77	29.13 ± 2.53	0.019	29.67 ± 3.16	28.74 ± 2.62	0.120	30.50 ± 2.82	29.17 ± 2.51	0.023
Pain begin age, years	15.14 ± 1.99	N/A	N/A	14.93 ± 2.12	N/A	N/A	15.03 ± 1.98	N/A	N/A
Pain duration year, years	5.14 ± 2.13	N/A	N/A	5.53 ± 2.22	N/A	N/A	5.29 ± 2.12	N/A	N/A
Pain degree	6.54 ± 1.09	N/A	N/A	6.77 ± 1.03	N/A	N/A	6.61 ± 1.10	N/A	N/A
Positive emotion
Pre-test^a	N/A	N/A	N/A	15.03 ± 5.93	16.45 ± 5.54	0.188	N/A	N/A	N/A
Post-test^a	N/A	N/A	N/A	13.13 ± 4.96	14.71 ± 5.69	0.304	N/A	N/A	N/A
p-value within group^b	N/A	N/A	N/A	0.088	0.059	N/A	N/A	N/A	N/A
Negative emotion
Pre-test^a	N/A	N/A	N/A	12.23 ± 2.54	11.39 ± 2.35	0.151	N/A	N/A	N/A
Post-test^a	N/A	N/A	N/A	12.67 ± 3.17	12 ± 3.54	0.155	N/A	N/A	N/A
p-value within group^b	N/A	N/A	N/A	0.771	0.297	N/A	N/A	N/A	N/A
BNQ
Pre-test^c	N/A	N/A	N/A	2.33 ± 0.42	2.42 ± 0.40	0.407	N/A	N/A	N/A
Post-test^c	N/A	N/A	N/A	3.11 ± 0.42	3.10 ± 0.46	0.988	N/A	N/A	N/A
p-value within group^d	N/A	N/A	N/A	<0.001	<0.001	N/A	N/A	N/A	N/A

PDM, primary dysmenorrhea; Ctrl, controls; BNQ, basic needs questionnaire. ^aMann–Whitney test; ^bWilcoxon test; ^cTwo-sample t-tests; ^dPaired-sample t-tests; M, mean value; SD, standard deviation; N/A, non-applicable.