TABLE 3.
Specific brain regions show significant group differences in functional connectivity with ACC.L/ACC.R/ACC for ISE-INCL, ESE-ISE, ESE-INCL contrasts.
| ROI | Peak location (AAL-90) | No. of voxels | Peak t-value | Peak coordinate in MNI space | Included other regions | PPI-parameter (β value) (mean ± SEM) | |||
| X | Y | Z | PDM | Ctrl | |||||
| ISE-INCL (PDM-Ctrl) | |||||||||
| ACC.L | N/A | 198 | 3.659 | 9 | –18 | –33 | Brainstem, CER4_5.L | 0.571 ± 0.312 | –1.095 ± 0.35 |
| ACC.R | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| ACC | N/A | 208 | 3.678 | 9 | –18 | –33 | Brainstem, PHIPP.R, AMYG.R, HIPP.R | 0.63 ± 0.309 | –1.08 ± 0.356 |
| ESE-ISE (PDM-Ctrl) | |||||||||
| ACC.L/ACC.R/ACC | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| ESE-INCL (PDM-Ctrl) | |||||||||
| ACC.L | PHIPP.L | 770 | 4.292 | –15 | 0 | –29 | INS.L, HIPP.L, PHIPP.R | –1.511 ± 0.251 | –3.21 ± 0.292 |
| IFGtriang.R | 556 | 3.897 | 39 | 33 | 18 | MFG.R, PUT.R, CAU.R, ACC.R, INS.R | –2.653 ± 0.312 | –4.382 ± 0.365 | |
| THA.R | 1076 | 3.94 | 6 | –12 | 20 | MCC.L, MFG.L, SFG.L, MCC.R, SFG.R, SMA.R, PreCG.L | –2.744 ± 0.348 | –4.561 ± 0.344 | |
| ACC.R | N/A | 579 | 4.484 | –15 | –15 | –30 | HIPP.L, PHIPP.L, | –1.119 ± 0.226 | –2.652 ± 0.267 |
| IFGtriang.R | 287 | 4.057 | 39 | 33 | 18 | MFG.R, IFGoperc.R, INS.R, PreCG.R | –2.498 ± 0.323 | –4.228 ± 0.34 | |
| HIPP.R | 241 | 3.839 | 30 | –36 | 0 | THA.R, THA.L, CAU.L | –2.727 ± 0.311 | –4.262 ± 0.278 | |
| SFG.R | 261 | 3.497 | 18 | 24 | 42 | MCC.L, MFG.L, SFG.L, SMA.R | –2.885 ± 0.399 | –4.771 ± 0.349 | |
| ACC | N/A | 652 | 4.478 | –15 | –15 | –30 | HIPP.L, PHIPP.L, PHIPP.R, | –1.14 ± 0.227 | –2.672 ± 0.269 |
| MFG.R | 489 | 4.21 | 42 | 33 | 21 | IFGtriang.R, IFGoperc.R, INS.R, PreCG.R | –2.489 ± 0.313 | –4.24 ± 0.355 | |
| HIPP.R | 391 | 3.934 | 30 | –36 | 0 | THA.R, THA.L, CAU.R, CAU.L | –2.707 ± 0.311 | –4.305 ± 0.308 | |
ACC, anterior cingulate cortex; ISE, implicit social exclusion; INCL, inclusion; ESE, explicit social exclusion; PDM, primary dysmenorrhea; Ctrl, controls; PPI, psychophysiological interaction; ROI, region of interesting; MNI, Montreal Neurological Institute; AAL, automated anatomical labeling atlas; CER4_5, lobule IV, V of cerebellar hemisphere; PHIPP, parahippocampal gyrus; AMYG, amygdala; HIPP, hippocampal gyrus; INS, insula; IFGtriang, inferior frontal gyrus, triangular part; MFG, middle frontal gyrus; PUT, putamen; CAU, caudate nucleus; ACC, anterior cingulate cortex; THA, thalamus; MCC, middle cingulate cortex; SFG, superior frontal gyrus; SMA, supplementary motor area; PreCG, precentral gyrus; IFGoperc, inferior frontal gyrus, opercular part; SEM, standard error of mean; L/R, left/right hemisphere; N/A, non-applicable.