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. 2021 Jun 16;9(6):e002118. doi: 10.1136/jitc-2020-002118

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.

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Stratification analysis of the performance of the DLS in prognosis prediction. (A) The DCB rates of the different subgroups of the MCC retrospective and prospective ICI-treated patients. (B) The PFS relative to the DLS and histology in the MCC retrospective and prospective ICI-treated patients. (C) The OS relative to the DLS and histology in the MCC retrospective and prospective ICI-treated patients. Note: HADC is short for HDLS ADC, meaning ADC patients with high DLS; LADC is short for LDLS ADC, meaning ADC patients with low DLS; HSCC is short for HDLS SCC, meaning SCC patients with high DLS; and LSCC is short for LDLS SCC, meaning SCC patients with low DLS, the high DLS versus low DLS defined by 0.55. P value was from log rank test. ADC, adenocarcinoma; DCB, durable clinical benefit; DLS, deeply learned score; ICI, immune checkpoint inhibitor; MCC, H Lee Moffitt Cancer Center and Research Institute; OS, overall survival; PFS, progression-freesurvival; SCC, squamouscell carcinoma.