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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Psychiatry Res. 2021 Mar 13;299:113870. doi: 10.1016/j.psychres.2021.113870

Table 1.

Amphetamine-type stimulant, cocaine, and any stimulant use and use disorder by adverse childhood experience score.

Adverse Childhood Experience (ACE) Scorea
Substance Variable 0 1 2–3 >=4
No.b %c (95% CI) No.b %c (95% CI) No.b %c (95% CI) No.b %c (95% CI)
Amphetamine-Type Stimulants
Lifetimed use
Yes 777 5.3% (4.8%, 5.8%) 595 7.9% (7.3%, 8.7%) 688 11.8% (10.8%, 13.0%) 654 17.6% (16.0%, 19.4%)
No 16,158 94.7% (94.2%, 95.2%) 8,024 92.1% (91.3%, 92.7%) 6,000 88.2% (87.0%, 89.2%) 3,360 82.4% (80.6%, 84.0%)
Past-year use
Yes 124 0.8% (0.7%, 1.0%) 85 1.2% (0.9%, 1.6%) 104 1.7% (1.4%, 2.1%) 95 2.5% (2.0%, 3.1%)
No 16,787 99.2% (99.0%, 99.3%) 8,523 98.8% (98.4%, 99.1%) 6,565 98.3% (97.9%, 98.6%) 3,898 97.5% (96.9%, 98.0%)
Lifetimed use disordere
Yes 111 0.7% (0.6%, 0.9%) 108 1.6% (1.3%, 1.9%) 163 2.8% (2.3%, 3.4%) 185 4.8% (4.0%, 5.7%)
No 16,849 99.3% (99.1%, 99.4%) 8,524 98.4% (98.1%, 98.7%) 6,535 97.2% (96.6%, 97.7%) 3,834 95.2% (94.3%, 96.0%)
Past-year use disordere
Yes 20 0.1% (0.1%, 0.2%) 20 0.2% (0.1%, 0.4%) 34 0.6% (0.4%, 0.8%) 38 1.0% (0.7%, 1.5%)
No 16,940 99.9% (99.8%, 99.9%) 8,612 99.8% (99.6%, 99.9%) 6,664 99.4% (99.2%, 99.6%) 3,981 99.0% (98.5%, 99.3%)
Cocaine
Lifetimed use
Yes 1,029 6.3% (5.8%, 6.8%) 834 10.4% (9.5%, 11.3%) 905 13.8% (12.8%, 14.9%) 775 19.8% (18.0%, 21.7%)
No 15,907 93.7% (93.2%, 94.2%) 7,782 89.6% (88.7%, 90.5%) 5,783 86.2% (85.1%, 87.2%) 3,240 80.2% (78.3%, 82.0%)
Past-year use
Yes 113 0.6% (0.5%, 0.7%) 93 0.9% (0.7%, 1.2%) 117 1.6% (1.2%, 2.1%) 96 2.3% (1.8%, 3.1%)
No 16,800 99.4% (99.3%, 99.5%) 8,506 99.1% (98.8%, 99.3%) 6,556 98.4% (97.9%, 98.8%) 3,910 97.7% (96.9%, 98.2%)
Lifetimed use disordere
Yes 197 1.2% (1.1%, 1.5%) 178 2.0% (1.7%, 2.4%) 244 3.6% (3.1%, 4.2%) 252 6.5% (5.6%, 7.6%)
No 16,763 98.8% (98.5%, 99.0%) 8,454 98.0% (97.6%, 98.3%) 6,454 96.4% (95.8%, 96.9%) 3,767 93.5% (92.4%, 94.4%)
Past-year use disordere
Yes 37 0.2% (0.1%, 0.3%) 28 0.3% (0.2%, 0.5%) 41 0.4% (0.3%, 0.6%) 46 1.1% (0.8%, 1.6%)
No 16,923 99.8% (99.7%, 99,9%) 8,604 99.7% (99.5%, 99.8%) 6,657 99.6% (99.4%, 99.7%) 3,973 98.9% (98.4%, 99.2%)
Any Stimulantf
Lifetimed use
Yes 1,349 8.6% (8.0%, 9.2%) 1,067 13.6% (12.6%, 14.6%) 1,160 18.3% (17.1%, 19.6%) 989 25.5% (23.6%, 27.6%)
No 15,585 91.4% (90.8%, 92.0%) 7,549 86.4% (85.4%, 87.4%) 5,528 81.7% (80.4%, 82.9%) 3,024 74.5% (72.4%, 76.4%)
Past-year use
Yes 208 1.2% (1.0%, 1.5%) 154 1.8% (1.5%, 2.2%) 191 2.8% (2.3%, 3.4%) 167 4.1% (3.3%, 5.0%)
No 16,691 98.8% (98.5%, 99.0%) 8,442 98.2% (97.8%, 98.5%) 6,471 97.2% (96.6%, 97.7%) 3,821 95.9% (95.0%, 96.7%)
Lifetimed use disordere
Yes 271 1.7% (1.5%, 2.0%) 250 3.1% (2.6%, 3.6%) 354 5.5% (4.8%, 6.2%) 371 9.2% (8.2%, 10.3%)
No 16,689 98.3% (98.0%, 98.5%) 8,382 96.9% (96.4%, 97.4%) 6,344 94.5% (93.8%, 95.2%) 3,648 90.8% (89.7%, 91.8%)
Past-year use disordere
Yes 55 0.3% (0.2%, 0.4%) 44 0.5% (0.3%, 0.7%) 70 1.0% (0.7%, 1.2%) 76 1.9% (1.4%, 2.5%)
No 16,905 99.7% (99.6%, 99.8%) 8,588 99.5% (99.3%, 99.7%) 6,628 99.0% (98.8%, 99.3%) 3,943 98.1% (97.5%, 98.6%)
a

Adverse childhood experience (ACE) score is calculated based on the number of exposures to 10 ACE categories.

b

Unweighted number of individuals

c

The percentages are weighted estimates.

d

Lifetime use indicates a respondent reporting ever use of the substance.

e

Use disorder is assessed based on self-reported questions that correspond to DSM-V diagnosis criteria.

f

Amphetamine-type stimulants and/or cocaine.

Source: National Epidemiological Survey on Alcohol and Related Conditions, United States, 2012–2013 (n = 36,309)