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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: J Mass Spectrom. 2020 Sep 21;55(12):e4614. doi: 10.1002/jms.4614

Figure 5:

Figure 5:

TIMS analysis of a whole-body mouse pup uncovers distinct spatial distributions of isobaric species indistinguishable by the mass spectrometer alone. Ion images were acquired at 50 μm spatial resolution with a 400 ms TIMS scan time on a prototype timsTOF fleX equipped with a MALDI ion source. (A) Ion image produced from a selected mobility region for [PC(34:3)+H]+. (B) Ion image produced from selected mobility region for [PC(32:0)+Na]+. (C) Ion image produced without mobility selection, demonstrating domination by the higher intensity [PC(32:0)+Na]+.This figure is adapted with permission from ref37, Spraggins, J.M. et al. Analytical Chemistry (2019). Copyright 2019 American Chemical Society.