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. 2021 Jun 17;16(6):e0253433. doi: 10.1371/journal.pone.0253433

Table 1. Comparison of demographics, clinical, and laboratory findings between COVID-19 patients with and without muscle loss.

Patients with muscle loss Patients without muscle loss P
Gendera (female/male) 16/27 30/77 0.328
Age (years)b (mean±SD) 73.4±10 56.4±14 <0.001
Fevera (yes/no) 39/4 98/9 0.542
Respiratory symptomsa (yes/no) 34/9 80/27 0.675
Gastrointestinal symptomsra (yes/no) 12/31 16/91 0.103
Other symtpomsa (yes/no) 6/37 19/88 0.637
Barthel Index (mean±SD) 54.4±33 85.1±26 <0.001
Hemoglobin (g/l)b (mean±SD) 11.5±2 13.2±2 <0.001
Red blood cells count (×1012·L−1)b (mean±SD) 3.9±1 4.6±1 <0.001
White blood cells count (×109·L−1)b (mean±SD) 9.4±7 7.2±4 0.019
C-reactive protein (mg/L−1)b (mean±SD) 71.5±71 44±48 0.009
Aspartate aminotransferase (U/L)b (mean±SD) 62.1±139 40.7±39 0.154
Alanine aminotransferase (U/L)b (mean±SD) 58.25±130 51.9±114 0.773
Alkaline phosphatase (U/L)b (mean±SD) 79.7±37.8 69.3±38 0.195
Lactate dehydrogenase (U/L)b (mean±SD) 335±163 265.8±116 0.008
Creatine phosphokinase (U/L)b (mean±SD) 147±156 124.8±144 0.457

aFisher’s exact test

bStudent’s t-test; applied level of significance p<0.05.