TABLE 1.
Effect of Triphala churna on oxidative stress parameters.
| Parameter group | MDA (nmol/mg protein) | GSH (μmole/mg protein) | Catalase (µmole of H2O2 decomposed/min/mg protein) | SOD (unit/mg protein) |
|---|---|---|---|---|
| Normal control | 2.50 ± 0.21 | 37.77 ± 2.24 | 0.128 ± 0.006 | 0.91 ± 0.07 |
| Diabetic control | 13.14 ± 1.00### | 22.11 ± 1.64### | 0.055 ± 0.004### | 0.38 ± 0.05### |
| Diabetic + triphala (250 mg/kg) | 7.43 ± 0.46*** | 26.82 ± 2.95 | 0.072 ± 0.004 | 0.57 ± 0.02 |
| Diabetic + triphala (500 mg/kg) | 5.34 ± 0.24*** | 31.56 ± 1.16* | 0.080 ± 0.006* | 0.62 ± 0.05* |
| Diabetic + triphala (1,000 mg/kg) | 2.91 ± 0.42*** | 34.05 ± 2.12** | 0.093 ± 0.006*** | 0.86 ± 0.05*** |
| F (DFn, DFd) | F (4, 25) = 62.74 | F (4, 25) = 8.452 | F (4, 25) = 28.22 | F (4, 25) = 19.41 |
All data is expressed as Mean ± SEM (n = 6). ### p < 0.001 when compared with normal control, *p < 0.05, **p < 0.01, ***p < 0.001 when compared with diabetic control.