Table 1:
Comparison of baseline patient characteristics by anticoagulation strategy during periods of severe thrombocytopenia. Abbreviations: IQR=interquartile range, BMI=body mass index (kg/m2), BMT=bone marrow transplant, PE=pulmonary embolism, VTE=venous thromboembolism, DVT=deep vein thrombosis, UE=upper extremity, LE=lower extremity, PCD=plasma cell dyscrasia, IVC=inferior vena cava. *Chi-squared test was used for all categorical variables and Wilcoxon Rank Sum test used to calculate p values for continuous variables.
| No Anticoagulation | Any Anticoagulation | P value* | |
|---|---|---|---|
| n (%) or Median (IQR) | n (%) or Median (IQR) | ||
| Total | 33 | 45 | |
| Age, years | 56 (46–66) | 54 (43–61) | 0.177 |
| BMI | 28 (24–29) | 30 (26–34) | 0.094 |
| Male | 18 (55) | 28 (62) | 0.642 |
| Malignancy | |||
| Lymphoma | 7 (21) | 15 (33) | 0.066 |
| Leukemia/MDS | 22 (67) | 18 (40) | |
| PCD | 4 (12) | 12 (27) | |
| BMT Status | |||
| None | 19 (58) | 10 (22) | 0.001 |
| Autograft | 5 (15) | 24 (53) | |
| Allograft | 9 (27) | 11 (24) | |
| Initial VTE | |||
| UE DVT | 23 (70) | 35 (78) | 0.021 |
| LE DVT | 6 (18) | 1 (2) | |
| PE | 3 (9) | 9 (20) | |
| Other | 1 (3) | 0 | |
| Time from VTE to PLT <50×109/L | |||
| 0 (concurrent) | 9 (27) | 14 (31) | 0.535 |
| 1–30 days | 10 (30) | 13 (29) | |
| 31–90 days | 5 (15) | 11 (24) | |
| >90 days | 9 (27) | 7 (16) | |
| Prior VTE | 1 (3) | 4 (9) | 0.389 |
| Recent Bleed (<1 month) | 2 (6) | 4 (9) | 0.691 |
| IVC filter | 3 (9) | 1 (2) | 0.305 |