Table 1.

Basal properties of POMC neurons in slices from mice treated for 7 d with LDN or saline

	Resting membrane potential (mV)	Membrane capacitance (pF)	Input resistance (MΩ)	sPSC frequency (Hz)	sPSC amplitude (pA)	AP threshold (mV)	AP frequency (Hz)
Saline mean ± SD	−39.44 ± 6.33 n = 10	23.65 ± 7.72 n = 32	820.8 ± 737.1 n = 32	8.789 ± 4.30 n = 33	59.86 ± 31.73 n = 33	−38.98 ± 5.78 n = 11	7.13 ± 4.08 n = 9
LDN mean ± SD	−41.39 ± 11.30 n = 11	19.38 ± 6.12 n = 34	743.7 ± 699.1 n = 34	6.185 ± 4.16 n = 32	42.82 ± 23.64 n = 31	−41.89 ± 6.25 n = 12	5.24 ± 5.76 n = 11
p	0.6355	0.0151	0.6642	0.0160	0.0183	0.2606	0.4190
t(df)	0.4818 (19)	2.498 (64)	0.4362 (64)	2.475 (63)	2.424 (62)	1.156 (21)	0.827 (18)

Membrane capacitance, sPSC frequency, and sPSC amplitude were all lower in the LDN group as compared with saline (p > 0.05). Values are expressed as mean ± SD; n represents cell numbers. Total slices for each group: (columns 2–5) same as cell numbers, (columns 1, 6, 7) saline = 10, LDN = 9. Total mice for each group: (columns 2–5) saline = 21, LDN = 19; (columns 1, 6, 7) saline = 5, LDN = 4.