Table 1. Patient characteristics.
| Sample population | IRA | IAA | P value | |
| n = 289 | n = 197 | n = 92 | ||
| Age, (mean (SD)) | 29.5 (16.3) | 31.9 (18) | 24.3 (9.6) | 0.0001 |
| Sex, n (%) | ||||
| Male | 138 (47.8) | 95 (48.2) | 43 (46.7) | 0.81 |
| Female | 151 (52.2) | 102 (51.8) | 49 (53.3) | |
| Mutation, n (%) | ||||
| Exon 15 | 96 (33.2) | 55 (27.9) | 41 (44.6) | 0.005 |
| Other mutations | 86 (29.7) | 57 (28.9) | 29 (31.5) | 0.69 |
| Missing | 107 (37.1) | 85 (43.2) | 22 (23.9) | |
| Comorbidities, n (%) | ||||
| Smoking | ||||
| Never | 221 (76.5) | 148 (75.1) | 73 (79.3) | 0.28 |
| Previous | 53 (18.3) | 13 (6.6) | 2 (2.2) | |
| Current | 15 (5.2) | 36 (18.3) | 17 (18.5) | |
| Pulmonary | 31 (10.7) | 21 (10.7) | 10 (10.9) | 0.96 |
| Cardiovascular | 51 (17.6) | 39 (19.8) | 12 (13.0) | 0.16 |
| Neurologic | 30 (10.4) | 19 (9.6) | 11 (12.0) | 0.55 |
| Hematologic | 7 (2.4) | 6 (3.0) | 1 (1.1) | 0.31 |
| Desmoid tumor, n (%) | 38 (13.1) | 22 (11.2) | 16 (17.4) | 0.14 |
| Number of preoperative colic adenomas (mean (SD)) | 316.5 (278.7) | 303.5 (269.6) | 334.4 (294.9) | 0.82 |
| Number of preoperative rectal adenomas (mean (SD)) | 34.1 (34.6) | 24.7 (33.9) | 52.8 (27.8) | 0.0001 |
| Adenocarcioma at diagnosis, n (%) | ||||
| Colorectal | 28 (9.7) | 21 (10.7) | 7 (7.6) | 0.41 |
| Rectal | 9 (3.1) | 3 (1.5) | 6 (6.5) | 0.02 |
| Operative technique, n (%) | ||||
| Laparoscopy | 97 (34.6) | 89 (45.2) | 8 (8.7) | 0.0001 |
| Open | 192 (65.4) | 108 (54.8) | 84 (91.3) |
IRA, ileorectal anastomosis; IAA, ileoanal anastomosis.