Table 2.
Ten major differential metabolites for future analysis.
| ID | Name_des | Formula | Molecular weight | RT (min) | FC | p-value | VIP | Up/down |
|---|---|---|---|---|---|---|---|---|
| ESI+ | ||||||||
| Com_962_pos | Eicosapentaenoic acid | C20 H30 O2 | 302.22 | 14.10 | 0.58 | 4.95E-03 | 2.28 | Down |
| Com_384_pos | Docosahexaenoic acid | C22 H32 O2 | 328.24 | 15.07 | 1.77 | 1.62E-06 | 1.60 | Up |
| Com_2412_pos | Docosapentaenoic acid | C22 H34 O2 | 330.26 | 15.24 | 2.36 | 6.97E-09 | 2.23 | Up |
| Com_1075_pos | Arachidonic acid | C20 H32 O2 | 304.24 | 15.13 | 1.50 | 3.85E-06 | 1.06 | Up |
| Com_7642_pos | α-Ketoglutaric acid | C5 H6 O5 | 146.02 | 1.40 | 1.18 | 1.22E-03 | 0.44 | Up |
| Com_332_pos | Phosphoric acid | H3 O4 P | 97.98 | 1.68 | 1.65 | 9.31E-07 | 1.80 | Up |
| ESI- | ||||||||
| Com_108_neg | Citric acid | C6 H8 O7 | 192.03 | 1.49 | 2.11 | 1.02E-09 | 3.43 | Up |
| Com_5332_neg | α-Ketoglutaric acid | C5 H6 O5 | 146.02 | 1.72 | 1.78 | 2.17E-09 | 2.00 | Up |
| Com_7586_neg | Genistein | C15 H10 O5 | 270.05 | 9.61 | 0.63 | 6.15E-03 | 1.17 | Down |
| Com_8251_neg | Daidzein | C15 H10 O4 | 254.06 | 9.10 | 0.52 | 4.12E-02 | 1.50 | Down |
| Com_740_neg | Phosphoric acid | H3 O4 P | 97.98 | 1.55 | 2.33 | 1.42E-08 | 4.31 | Up |
| Com_783_neg | 2-Furoic acid | C5 H4 O3 | 112.02 | 1.50 | 2.25 | 1.97E-06 | 3.15 | Up |
FC, fold change (GDM case/control). VIP, variable importance in the projection. ESI+, positive ion mode; ESI-, negative ion mode.