Table 3.

Passage history, FCS deletion levels and in vivo outcomes of Washington 01 stocks.

Cell line used	Passage number					Model species
	1	2	3	4	5	Hamster	Primate
Vero (CCL-81)	<1%a	<1%a	<1%a
Vero E6 (CRL-1586)				<1%a,b	10–18%d	10–20% weight loss	Low viral load
Vero E6 (CRL-1586)				<16c	58–78%	No weight loss	Low viral load

^aNo deletions detected in over 99% of the reads spanning the FCS region.

^bThis P4 stock is identified by BEI as NR-52281, Lot 70033175.

^cThis P4 stock is identified by BEI as NR-52281, Lot 70036318.

^dVero propagated challenge stock referenced in the text.