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. 2021 Jun 17;12:3727. doi: 10.1038/s41467-021-24080-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Virogram showing the near full-length proviral genomes recovered from eight ART-treated individuals. Proviral genomes were reconstructed using a 5-amplicon, 2-amplicon, or 4-amplicon PCR approach. Corresponding integration sites (IS) are indicated at the right-hand side of each proviral genome. Cancer-related genes are indicated with an asterisk. b Heatmap of the deletions in the 5′ UTR region, including the Ψ packaging signal. The second-round forward primers for the 2-amplicon (F591) and 5-amplicon (U5-638F) NFL PCR approach are annotated with arrows on the heatmap. Proviruses with a deletion spanning the U5-638F primer are indicated with a triangle at the left-hand side of each provirus. MSD major splice donor, CD cryptic donor. c Memory subset distribution of clonal p24-producing cells. The number of cells within each clone is indicated at the left-hand side of each horizontal bar. TCM central memory T cell, TTM transitional memory T cell, TEM effector memory T cell.