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. 2021 Jun 17;11:12763. doi: 10.1038/s41598-021-91928-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of TGF-β on growth inhibition induced by atorvastatin in NCI-H322M cells. (A) Overview of experimental procedures. The group treated with atorvastatin post TGF-β1 induction is designated as TGF-β (+). PBS-treated control is designated as TGF-β (−). (B) Cell number in TGF-β (+) group with respect to cell number in TGF-β (−) control cells that was set to 100%. Each value represents mean ± SD (n = 3). Measurement values for each group are compared using the Bonferroni-Dunn post-hoc tests. *p < 0.05, **p < 0.01, with respect to each control group.