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The human gut xenograft model system. Human 12–18 week-old fetal gut (A,B) was transplanted subcutaneously into SCID mice (C; black arrows) and allowed to develop over 12–16 weeks into normal human small intestine or colon (D; black arrows). Microscopic images of formalin-fixed paraffin-embedded and H&E stained tissue sections of human fetal gut (B) and fully developed small intestine (E) and colon (F) transplant. Scale bars 200 µm.
