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. 2021 Jun 17;12:3710. doi: 10.1038/s41467-021-23959-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Results of cell compatibility assay for the custom-printed sensor array with heart myoblast (H9C2) cells in a 24-well plate, as measured using a colorimetric assay kit (n = 3 per group). b Representative histological cross-sectional views of the murine cardiac tissues that were stained with both hematoxylin-eosin (H&E; left panel) and Masson’s trichrome (MTC; right panel) on day 14 post-implant of the custom-printed sensor array. c Z-stack fluorescence images of a BSA-FITC (6 mg/ml) coated on the printed device as compared to control groups made of the SE 1700 ink and the Sylgard 184 ink and prepared on a pristine glass, from upper left to bottom right clockwise. d Results of one-way ANOVA tests with Bonferroni correction (n = 5 per group). Fluorescence intensity of pristine glass and sylgard 184 is shown as average ± standard deviation (^**p = 3.4 × 10⁻⁷, 4.1 × 10^-4), versus printed device. e Representative ultrasound images of the left ventricle of a murine heart on 0, 1, 7, and 14 days implantation of the custom-printed sensor array. f Results of the ejection fraction of the murine heart post-implant.