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. 2021 Jun 4;14:690858. doi: 10.3389/fnmol.2021.690858

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Copyright © 2021 Wu, Su, Zhang, Zhang, Feng, Ji and Tan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of TC-I on the sensory and motor behaviors following oxaliplatin treatment. The administration of oxaliplatin, the schedule for TC-I (10 mg/kg, ip) treatment (same to the Retigabine treatment), the testing schedule for different types of behaviors were described in the Legend of Figure 3. (A) Paw withdrawal threshold to Von-Frey filament; (B) Score of withdrawal response to acetone; (C) Paw withdrawal latency to radiant heat; and (D) Time stayed on rod at different speeds in rotarod tests (n = 6 for all groups). **, P < 0.01; ****, P < 0.0001; two-way repeated measure ANOVA.