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. 2021 Jun 4;8:586900. doi: 10.3389/fmed.2021.586900

Table 4.

Network meta-analysis of FEV1% predicted.

Control 5.90
(−5.74, 17.54)
6.98
(−5.12, 19.08)
−1.22
(−13.32, 10.88)
3.68
(−8.38, 15.73)
2.84
(−8.52, 14.21)
−4.46
(−15.59, 6.67)
4.98
(−5.72, 15.67)
0.52
(−9.94, 10.97)
−0.81
(−11.52, 9.90)
−5.90
(−17.54, 5.74)
AT 1.08
(−15.71, 17.86)
−7.12
(−23.91, 9.66)
−2.22
(−18.98, 14.53)
−3.06
(−19.32, 13.21)
−10.36
(−26.47, 5.75)
−0.92
(−16.73, 14.88)
−5.38
(−21.03, 10.26)
−6.71
(−22.53, 9.10)
−6.98
(−19.08, 5.12)
−1.08
(−17.86, 15.71)
Mx + Tx −8.20
(−13.93 to −2.47)*
−3.30
(−11.20, 4.60)
−4.13
(−10.93, 2.67)
−11.44
(−17.84 to −5.03)*
−2.00
(−8.33, 4.33)
−6.46
(−13.23, 0.31)
−7.79
(−13.42 to −2.16)*
1.22
(−10.88, 13.32)
7.12
(−9.66, 23.91)
8.20
(2.47, 13.93)*
Mx 4.90
(−3.00, 12.80)
4.07
(−2.73, 10.87)
−3.24
(−9.64, 3.17)
6.20
(−0.13, 12.53)
1.74
(−5.03, 8.51)
0.41
(−5.22, 6.05)
−3.68
(−15.73, 8.38)
2.22
(−14.53, 18.98)
3.30
(−4.60, 11.20)
−4.90
(−12.80, 3.00)
EA + Tx −0.83
(−7.55, 5.89)
−8.14
(−14.46 to −1.81)*
1.30
(−4.95, 7.55)
−3.16
(−9.85, 3.53)
−4.49
(−10.03, 1.05)
−2.84
(−14.21, 8.52)
3.06
(−13.21, 19.32)
4.13
(−2.67, 10.93)
−4.07
(−10.87, 2.73)
0.83
(−5.89, 7.55)
WA + Tx −7.31
(−12.21 to −2.40)*
2.13
(−2.63, 6.90)
−2.33
(−7.70, 3.04)
−3.66
(−7.46, 0.15)
4.46
(−6.67, 15.59)
10.36
(−5.75, 26.47)
11.44
(5.03, 17.84)*
3.24
(−3.17. 9.64)
8.14
(1.81, 14.46)
7.31
(2.40, 12.21)
WA 9.44
(5.23, 13.65)
4.98
(0.14, 9.81)
3.65
(0.59, 6.70)
−4.98
(−15.67, 5.72)
0.92
(−14.88, 16.73)
2.00
(−4.33, 8.33)
−6.20
(−12.53, 0.13)
−1.30
(−7.55, 4.95)
−2.13
(−6.90, 2.63)
−9.44
(−13.65, 5.23)*
A + Tx −4.46
(−8.52 to −0.40)*
−5.79
(−8.68 to −2.90)*
−0.52
(−10.97, 9.94)
5.38
(−10.26, 21.03)
6.46
(−0.31, 13.23)
−1.74
(−8.51, 5.03)
3.16
(−3.53, 9.85)
2.33
(−3.04, 7.70)
−4.98
(−9.81 to −0.14)*
4.46
(0.40, 8.52)
A −1.33
(−5.09, 2.43)
0.81
(−0.90, 11.52)
6.71
(−9.10, 22.53)
7.79
(2.16, 13.42)
−0.41
(−6.05, 5.22)
4.49
(−1.05, 10.03)
3.66
(−0.15, 7.46)
−3.65
(−6.70 to −0.59)*
5.79
(2.90, 8.68)
1.33
(−2.43, 5.09)
Tx

Estimates are presented as mean difference (MD) and 95% confidence interval. For the part in the upper right, the estimate of treatment effectiveness should be read as column-defining treatment compared to the row-defining treatment. An MD of more than 0 favors the treatment in the column in improving FEV1%. Blue grids indicate treatment in column better than treatment in row.

*

Statistically significant.