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. 2021 Jun 17;19:89. doi: 10.1186/s43141-021-00192-5

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — The regulatory network of the involved players during the onset of tuber development in potato. StSP6A protein and StBEL5 mRNA are the molecular signals in tuber development. POTH1 is a negative regulator in GA signaling during the tuberization stage. GA acts as a tuberization repressor and StSP6A and StBEL5 play roles as tuberization promoters. Auxin and CK promote tuber development. StSP6A protein and StBEL5 RNA are considered long-distance tuberization signals, moving through the phloem from the leaf to the stolon. StGA20ox delayed tuber development in potato by increasing GA at this stage. StGA2ox1 expression inhibits tuber development