TABLE 2.

Model size at various stages of construction (E) refers to iMSC-E-1972, (O) refers to iMSC-O-1900, and (A) refers to the iMSC-A-2036.

Model	Genes	Reactions	Metabolites
Recon3D	3697	13543	8399
Base Model	2280	9151	4900
GIMME Models (medium and growth and transcriptomic)		6693(E) 6061(O) 6933(A)	3792(E) 3472(O) 3884(A)
Corrected Models (GIMME plus literature)		6741(E) 6134(O) 7006(A)	3830(E) 3526(O) 3939(A)
Final Models (Corrected plus metabolomics)	1972(E) 1900(O) 2036(A)	6600(E) 5975(O) 6876(A)	3740(E) 3428(O) 3855(A)
iMSC1255 model (used for comparison)	1259 (E)	2288 (E)	1850 (E)