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. 2021 Jun 4;9:642681. doi: 10.3389/fcell.2021.642681

TABLE 3.

Showing subsystems that have a significantly overrepresented (adjusted p-value < 0.05) number of more active reactions in the relevant model compared to the other differentiation lineage in the case of osteogenesis/adipogenesis or compared to the two differentiation models in the case of expansion.

Expansion
Adjusted p-Value Enriched set size Total set size Groups Increased
0.000254 98 1368 Exchange/demand reaction
0.001831 65 961 Fatty acid oxidation
0.003348 9 242 Cholesterol metabolism
0.003348 9 240 Fatty acid synthesis
0.003348 1 105 Transport, lysosomal
0.003348 25 453 Transport, mitochondrial
0.006098 3 133 Sphingolipid, metabolism
0.011893 7 185 Bile acid synthesis
0.017589 11 47 Vitamin A metabolism
0.019096 5 12 Biotin metabolism
Osteogenesis
Adjusted p-Value Enriched set size Total set size Groups Increased
7.09E-07 12 961 Fatty acid oxidation
8.6E-06 28 1368 Exchange/demand reaction
Adipogenesis
Adjusted p-Value Enriched set size Total set size Groups Increased
1.64E-05 26 1368 Exchange/demand reaction
0.000253 16 961 Fatty acid oxidation
0.012651 1 240 Fatty acid synthesis